Louisville vs Notre Dame 2/16/2025 College Basketball Picks

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Louisville vs Notre Dame Prediction

Louisville vs Notre Dame Game Information

What: Louisville vs Notre Dame 2/16/2025 College Basketball Picks
When: Sunday, February 16, 2025 at 8:00 EST/5:00 PST
Where: Purcell Pavilion, South Bend, Indiana
Louisville vs Notre Dame Line: Louisville -6.5
Total: 145.5
TV: ACC Network

Louisville vs Notre Dame Preview

Louisville (19-6, 12-2 in ACC) heads to South Bend, Indiana on Sunday evening to play Notre Dame (11-13, 5-8 in ACC) at Purcell Pavilion in this ACC Conference matchup. In their last 5 games, the Cardinals are 4-1, beating Wake Forest by 13 (72-59), losing at Georgia Tech by 7 (77-70), and then winning their last 3 against Boston College by 28 (84-56), Miami Florida by 10 (88-78), and at NC State by 25 (91-66). In their last 5, the Fighting Irish are 2-3, beating Georgia Tech by 3 (71-68), losing 3 straight to Miami Florida by 6 (63-57), at Florida State by 7 (67-60), and Virginia Tech by 2 (65-63), before losing at Boston College by 3 in 2 OT (97-94).

 

 

 

Futures Book Look: Online sportsbook DraftKings currently has Louisville priced at 75/1 to win the 2025 NCAA Basketball Tournament with Notre Dame longshots at 300/1. Duke (+390), Auburn (+390), Houston (+850), Alabama (+950), Florida (11/1), Iowa State (15/1), Tennessee (17/1), Purdue (30/1) and St. John’s (30/1) are the other top Favorites to win the NCAAB championship. The 2025 NCAA Division I Men’s Basketball Tournament tips off on March 19-20 with the First Four with the First Round starting on March 21-22. The Final Four will be on Saturday, April 5 at the Alamodome in San Antonio, Texas with the Championship Game on Monday, April 7.

Louisville Looks to Keep the Heat on Duke, Clemson 

Louisville (15-10-0 ATS, 9-16-0 O/U) can still catch Duke (14-1 in ACC) in the ACC Conference Regular Season race, and the Cardinals (-300) should prevail here vs the Dunking Leprechauns in the state that has basketball and IndyCar racing in its blood. Louisville has some great Roster depth in G Chucky Hepburn (15.0 PPG, 6.2 RPG, 6.2 APG, 2.3 SPG), G Terrence Edwards (14.9 PPG, 4.0 RPG, 2.8 APG), G Reyne Smith (14.4 PPG, 3.1 RPG), G J’Vonne Hadley (12.5 PPG, 7.2 RPG), F Kasean Pryor (12.0 PPG, 6.1 RPG, 2.1 APG), F James Scott (7.1 PPG, 6.4 RPG), F Noah Waterman (6.1 PPG, 3.8 RPG), and F Aboubacar Traore (5.6 PPG, 5.1 RPG). The shooting of Forward Scott (75.7%), who has at least four perfect (100%) shooting games has been absolutely otherworldly. The oft-underappreciated Cardinals average 79.7 PPG (Tied-#56) while allowing 69.3 PPG and average 38.3 RPG (#58) and 14.5 APG (Tied-#138). Saturday’s Bracketology by ESPN’s Joe Lunardi has the Cardinals projected as a No. 7 seed in the Tournament.

Louisville Betting Trends

  • Louisville is 9-1 SU in its last 10 games overall
  • The Under is 4-1-0 in Louisville’s last 5 games overall 
  • The Under is 21-11 in its last 32 games (+9.05 Units, 26% ROI)
  • The Cardinals are 7-3-0 ATS in their last 10 games overall
  • Louisville’s is 10-3 on the Moneyline in its last 13 (+7.85 Units, 53% ROI)

Notre Dame Won’t Be Happy Come St. Patrick’s Day 

Notre Dame (10-12-0 ATS, 11-13-0 O/U) is led in scoring by G Markus Burton (21.3 PPG, 3.5 RPG, 2.9 APG), F Tae Davis (15.8 PPG, 5.6 RPG, 2.0 APG), G Braeden Strawberry (13.8 PPG, 3.0 RPG), G Matt Allocco (9.4 PPG, 4.6 RPG, 3.0 APG), and F Kebba Njie (6.7 PPG, 6.4 RPG), but after that, this team is pretty toothless. The Fighting Irish (+240 Moneyline) average 14.0 PPG (#336) from the Bench, and when St Patrick’s Day (March 17) rolls around in a month and the whole sports world is looking at the Big Dance, Notre Dame will be crying in its green beer and likely shooting shamrocks in the NIT or CBI. The Fighting Irish average 73.8 PPG (Tied-#212) and allows 70.7 PPG with 35.7 Rebounds Per Game (#194) and 12.0 Assists Per Game (#345).

Notre Dame Betting Trends

  • Notre Dame is 4-6-0 SU in its last 10 games overall
  • The Fighting Irish are 8-3 at Home this 2024-25 NCAAB season, 3-7 on Road
  • The Under is 7-3-0 in Notre Dame’s last 10 games
  • Notre Dame has played 7 Road games in its last 10 overall
  • The Under is 4-0-0 in the Fighting Irish’s last 4 Home games

Louisville vs Notre Dame Prediction

In the last 10 series meetings, Louisville is 6-4 SU, but Notre Dame has won the last 4 meetings (after Louisville won 6 straight) and gone 3-1-0 ATS. Both schools are 5-5-0 in the ATS market over that span with the Under a powerful 8-2-0 in the series, getting the money the last 3 straight times and the last 3 in South Bend. So this Louisville vs Notre Dame NCAAB pick can’t help but look at the Total market with all of these solid-as-a-rock Under Trends we just handicapped:

 

  • The Under 4-1-0 last 5 Louisville games
  • The Under 21-11 in its last 32 Louisville games
  • The Under 4-0-0 last 4 Notre Dame Home games 
  • The Under 7-3-0 last 10 Notre dame games
  • The Under 8-2-0 last 10 in this series overall
  • The Under 3-0-0 last 3 in series at Notre Dame

 

Shop around for the best Totals number as there are currently 145.5’s in the market at most major online sportsbooks late Saturday (FanDuel, Caesars, BetMGM, DraftKings). 

Kevin’s Prediction: Louisville-Notre Dame Under 145.5

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