Pittsburgh Panthers vs Louisville Cardinals 10-22-22

Pittsburgh Panthers vs Louisville Cardinals 10/22/2022 Picks Predictions Previews

Pittsburgh Panthers vs Louisville Cardinals 10/22/2022 Picks Predictions Previews


The Pittsburgh Panthers will go against the Louisville Cardinals in NCAAF action in Cardinal Stadium, KY, on Saturday, October 22, 2022, at 8:00 PM ET.


The Pittsburgh Panthers enter this game with a 4-2 record thus far this year. The Panthers defeated the Virginia Tech Hokies 45-29 in their most recent game, which they played against each other.


Kedon Slovis completed 15 of 28 passes for 170 yards in the air. His quarterback rating was 97.4, and he finished the game with just one interception.


Israel Abanikanda led the Panthers’ running attack (8.9 yds per carry) with 36 carries for 320 yards. They ran 71 plays for 496 yards at the game’s conclusion. 


The Pittsburgh Panthers averaged 7.6 yards per attempt when running the ball with 43 separate attempts and 326 yards gained.


The Panthers’ rushing defense allowed 126 yards on 30 attempts or 4.2 yards per rush allowed. Pittsburgh allowed 25 pass completions on 47 attempts for 277 yards with a completion rate of 53.2%.


  • The Pittsburgh Panthers are 2-5 ATS in their last 7 matches. 
  • The total went OVER in 4 of Pittsburgh’s last 6 matches. 
  • The Pittsburgh Panthers are 13-4 SU in their last 17 matches.

More College Football Picks Predictions Previews

Chat with our Live Handicapper to Know More about the Game.

Pittsburgh Panthers vs Louisville Cardinals Predictions 10/22/2022


The Cardinals enter the game with a 3-3 record thus far this year. The Cardinals defeated the Virginia Cavaliers 34-17 the last time they played on the field, returning home triumphant.


Brock Domann (1 TD) finished the game with 275 yards on 17 of 30 passes while maintaining a 131.3 quarterback rating. His average yards per throw attempt was 9.2, and he threw two interceptions.


For Louisville, Trevion Cooley carried the ball 18 times for a total of 77 yards, averaging 4.3 yards per attempt.


Louisville finished the game with 198 yards on 46 runs, averaging 4.3 yards per tote. The Cardinals ran 76 plays for a total of 473 yards in the game (6.2 yards per play).


A completion rate of 70.6% was permitted by the Cardinals’ secondary, resulting in 313 yards on 24 out of 34 passes. Louisville surrendered 6 yards on 25 running attempts (0.2 yds per rush).


  • The total went OVER in 6 of Louisville’s last 9 matches. 
  • The total went UNDER in 6 of Louisville’s last 8 matches against Pittsburgh.
  • The Louisville Cardinals are 13-7 SU in their last 20 matches at home.

Pittsburgh Panthers vs Louisville Cardinals. The NCAAF pick for this game is the Pittsburgh Panthers. Last year, the Pittsburgh Panthers prevailed in this matchup, and they now appear to be the superior club.


Pittsburgh has a more evenly-matched lineup and a potent defense. Israel Abanikanda, a running back, hopes to expand on his successful season, which included 12 touchdowns.


The Pittsburgh Panthers will win to a predicted score of 35-27.


College Football Free Premium Picks Predictions. This week’s entire college football premium pick predictions against the spread are free right now at 1-888-711-4311 or text the word WINBIG to 760-670-3130 to receive them. Included are Best Bets, Parlays and Halftime winners for this week free of charge.

Pittsburgh Panthers vs Louisville Cardinals 10/22/2022 Picks Predictions Previews

NCAAF Starting Time: 8:00 PM (EDT)


Location: Cardinal Stadium, KY


Date: Saturday, October 22, 2022


TV: ACC Network Extra


NCAAF Odds: Pittsburgh Panthers +2.5


NCAAF Totals: 56


Click Here For More College Football Video Free Picks