Chicago Cubs vs Pittsburgh Pirates 9-25-22

Chicago Cubs vs Pittsburgh Pirates 9/25/2022 Picks Predictions Previews

Chicago Cubs vs Pittsburgh Pirates 9/25/2022 Picks Predictions Previews


The Chicago Cubs will play against the Pittsburgh Pirates at PNC Park, PA on Sunday, September 25, 2022, at 1:35 PM ET.


Chicago earned their fourth straight road victory Friday night after surviving a back-and-forth contest and taking the lead for good in the eighth inning.


The Cubs were 22.5 games down of the Cardinals in the NL Central heading into Saturday. They are no longer in the running for the playoffs. Chicago ranks 3rd in the National League Central division at 66-86.


Cubs pitcher Adrian Sampson is on the mound for his nineteenth appearance and the seventeenth start of the season. He enters the game with a record of 2-5, a 3.35 ERA, a 1.286 WHIP, 24 walks, and 61 strikeouts in 88.2 innings pitched.


Sampson’s most recent start, on the road against the Marlins on Tuesday, did not affect the decision. Sampson has a 1-0 record, a 1.00 ERA, a 1.11 WHIP, five walks, and seven strikeouts in 18 innings of work over his last three starts. 


  • The total went UNDER in 12 of the Chi Cubs’ previous 16 matches. 
  • The Chicago Cubs are 4-1 SU in their last 5 games. 
  • The Cubs are 4-1 SU in their last 5 contests against the Pirates.

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Chicago Cubs vs Pittsburgh Pirates Predictions 9/25/2022


The Cubs prevailed for the second night in a row in this series, handing Pittsburgh their eighth straight defeat. The Pirates were 33.5 games behind the Cardinals for first place in the NL Central heading into Saturday.


For the seventh consecutive year and the 27th time in the past 30 years, they were ruled out of the playoff race.


Pittsburgh recorded six hits on Thursday, with Bryan Reynolds (two runs, two RBI) being the only player to collect two. The Pirates sit 5th in the NL Central with a win/loss slate of 56-96.


Luis Ortiz will make his third start of the season for the Pirates in this game. He entered the game with no records, 10.2 innings pitched a 0.84 ERA, a 0.844 WHIP, five walks, and 10 strikeouts.


In a game the Pirates lost 9-8 in a walk-off, he pitched five innings, surrendering two runs (one earned) on three hits, two walks, and five strikeouts. Ortiz will take on the Cubs for the first time in his third major league start overall.  


  • The total went OVER in 4 of the Pirates’ last 6 matches. 
  • The PittsburghPirates are 1-8 SU in their previous 9 games. 
  • The total went UNDER in 4 of the team’s previous 5 meetings against the Chi Cubs.

Chicago Cubs vs Pittsburgh Pirates. The MLB pick for this game is the Chicago Cubs. Chicago defeated Pittsburgh in each of the last four encounters.


The Cubs triumphed in each of their previous four games overall, five of their previous six road games against right-handed starting pitchers, and four of their previous five games against opponents with winning percentages under.400.


Adrian Sampson, the starting pitcher for Chicago, made five straight quality starts, going 26-13 innings while giving up a total of five runs on 24 hits. The Chicago Cubs are predicted to win by a score of 5-4.


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Chicago Cubs vs Pittsburgh Pirates 9/25/2022 Picks Predictions Previews

MLB Starting Time: 1:35 PM (EDT)


Location: PNC Park, PA 


Date: Sunday, September 25, 2022




MLB Odds: Chicago Cubs -105 


MLB Totals: 8


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