Chicago Cubs vs Miami Marlins 9-21-22

Chicago Cubs vs Miami Marlins 9/21/2022 Picks Predictions Previews

Chicago Cubs vs Miami Marlins 9/21/2022 Picks Predictions Previews


The Chicago Cubs will face off with the Miami Marlins at LoanDepot Park, FL on Wednesday, September 21, 2022, at 6:40 PM ET.


The NL East-leading Mets were defeated by Chicago in three games in New York last week, capping up one of its greatest series of the year.


With a 2-1 victory over Colorado on Friday, the Cubs increased their winning streak to four games, but they went on to drop the next two games in the series.


They lost against Miami 10-3 on Monday, continuing their losing streak. They have seven games left on their road trip, which will be completed this weekend with four games versus the Pirates.


Next week, Chicago will make its final home appearance of the year with a six-game homestand. The Cubs are already out of the running for the postseason. 


Drew Smyly, a left-handed pitcher, was initially scheduled to start for Chicago on Wednesday but was scratched on Tuesday due to shoulder discomfort.


In this game, Marcus Stroman starts after moving up a day in the rotation. He pitched seven innings against Colorado, giving up one run on three hits and two walks.


Before surrendering a solitary home run, Stroman went six scoreless innings. Since the All-Star break, he pitched 64 innings with an ERA of 2.95 and a WHIP of 1.20. 


  • The total went UNDER in 10 of the Chi Cubs’ previous 12 matches. 
  • The Chicago Cubs are 4-9 SU in their last 13 contests against the Marlins.
  • The Cubs are 4-1 SU in their last 5 games on the road.

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Chicago Cubs vs Miami Marlins Predictions 9/21/2022


Miami enjoyed a promising start to the season, as they were only five games out  from .500 at the All-Star break. Since then, the Marlins had a lot of difficulty, never managing to win more than two straight games.


After winning the first game of this series against Chicago 10-3 on Monday and the final game of their series against Washington 3-1 on Sunday, they have a chance to replicate that on Tuesday night.


Miami is in the midst of a six-game homestand that will come to a close this weekend with three games versus Washington. Like the Cubs, the Marlins’ chances of making the postseason were already effectively eliminated. 


Jesus Luzardo, a left-handed pitcher, will make his Miami debut on Wednesday. Last Friday against Washington, he pitched for more than six innings while giving up two runs on five hits and a walk.


In his last eight appearances, Luzardo had six quality starts, recording a 3.59 ERA and 1.07 WHIP. This season, he has a 3.75 ERA, 91 strikeouts, and a record of 3-7. 


  • The Miami Marlins are 6-14 SU in their last 20 games. 
  • The total went UNDER in 5 of Miami’s previous 6 meetings against the Chi Cubs. 
  • The Marlins are 4-10 SU in their last 14 matches at home.

Chicago Cubs vs. Miami Marlins. The MLB pick for this game is the Miami Marlins. Willson Contreras of the Chicago Cubs participated in live batting practice on Tuesday and could make a comeback later this month.


Chicago is 23rd in runs scored and 16th in OPS through 148 games. Miami is currently ranked 27th in both runs scored and OPS for the season. Pick the underdog. The Miami Marlins are expected to triumph by a score of 3-2.


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Chicago Cubs vs Miami Marlins 9/21/2022 Picks Predictions Previews

MLB Starting Time: 6:40 PM (EDT)


Location: LoanDepot Park, FL 


Date: Wednesday, September 21, 2022




MLB Odds: Miami Marlins -120


MLB Totals: 6.5


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