St Louis Cardinals vs Pittsburgh Pirates Game 1 5-21-22

St Louis Cardinals vs Pittsburgh Pirates Game 1 5/21/2022 Picks Predictions Previews

St Louis Cardinals vs Pittsburgh Pirates Game 1 5/21/2022 Picks Predictions Previews


The St. Louis Cardinals will go against the Pittsburgh Pirates in MLB Game 1 action in PNC Park, PA, on Saturday, May 21, 2022, at 6:35 PM ET.


The Cardinals entered into this series with three straight losses to the Mets. The 7-6 defeat on Thursday was decided by a Pete Alonso walk-off 9th-inning homer. They are still in the second position in the National League Central and have a chance to close the gap in this series.


The Cardinals have a strong offense, generating 4.53 runs per game, good for 10th in the league. They hit.249 as a club, which is good for 5th in baseball, and their slugging percentage is good for 10th.


With 9 home runs, 31 RBIs, and a .297 batting average, Nolan Arenado leads the squad. Paul Goldschmidt is hitting .329 with six home runs and 27 RBIs.


On Saturday, the Cardinals will start Matthew Liberatore. The left-handed pitcher will make his main league debut after being called up from Triple-A Memphis. At Memphis, Liberatore was 3-3 with a 3.83 ERA. He was 0-1 with a 4.26 ERA in three spring training outings with the Cardinals, striking out 7 and walking 4.


The Cardinals have a 3.67 team ERA, which ranks them 12th in the Majors. The Cardinals’ bullpen has a 3.73 ERA, which ranks them 18th in the league.


  • The total went Over in 4-0 of the Cardinals’ last 4 road matches with the total set at 9.0-10.5.
  • The Cardinals are 23-5 in the previous 28 meetings in Pittsburgh.
  • St. Louis is 4-0 in Mikolas’ last 4 starts during game 2 of a series.

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St Louis Cardinals vs Pittsburgh Pirates Game 1 Predictions 5/21/2022


The Pirates are currently in third place in the National League Central, but they have a chance to pick up some matches against the Cardinals in this series.


The Pirates entered this series having lost two of three to the Cubs. The Pirates’ offense was abysmal, generating 3.3 runs per game, which ranks them 29th in MLB.


Their team batting average is.224, and their slugging percentage is 28th. With a .289 batting average, Ke’Bryan Hayes tops the Pirates, while Daniel Vogelbach has six home runs and 14 RBIs while hitting .252.


On Saturday, the Pirates will start Jose Quintana. Quintana has a 1.19 ERA in seven starts this season. In 37 innings of action, he has 30 strikeouts and 14 walks. Quintana pitched seven shutout innings in his last start, surrendering only three hits while striking out five and walking one batter.


In the Pirates’ 1-0 victory, he received a no-decision. In 11 appearances against the Cardinals, the left-hander is 5-3 with a 4.39 ERA and 54 strikeouts.


The Pirates have a 4.68 team ERA, which ranks them 27th in the league. The bullpen’s ERA is 4.15, which ranks 25th in the league.


  • The total went Under in 4-0-1 of the Pirates’ last 5 overall.
  • The total went Under in 3-0-1 of Quintana’s last 4 starts as a home underdog.
  • The total went Under in 4-0-1 of the Pirates’ last 5 matches as an underdog.

St. Louis Cardinals vs Pittsburgh Pirates. The MLB pick for this game is the Pittsburgh Pirates. Don’t tell the Pirates, but the NL Central appears to be a two-team contest between the Brewers and Cardinals.


Pittsburgh is a couple of matches under .500 in third place, but a series win this weekend might help them cut the gap on the Cardinals.


I believe they will win this game on Saturday due to a good pitching matchup with Quintana on the mound. Quintana was the Pirates’ greatest pitcher this season, with a 2.19 ERA and a 7-inning outing in which he surrendered no runs.


There’s too much ambiguity in the Cardinals’ lineup since they’re starting a rookie. The Pittsburgh Pirates will win to a predicted score of 5-4.


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St Louis Cardinals vs Pittsburgh Pirates Game 1 5/21/2022 Picks Predictions Previews

MLB Starting Time: 6:35 PM (EDT)


Location: PNC Park, PA


Date: Saturday, May 21, 2022




MLB Odds: Pittsburgh Pirates +116 


MLB Totals: 8.5


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