Chicago White Sox vs New York Yankees 5-21-22

Chicago White Sox vs New York Yankees 5/21/2022 Picks Predictions Previews

Chicago White Sox vs New York Yankees 5/21/2022 Picks Predictions Previews


The Chicago White Sox will meet with the New York Yankees in MLB action in Yankee Stadium, NY, on Saturday, May 21, 2022, at 1:05 PM ET. After Friday night’s rainout, the White Sox are even at 19-19 and are only three matches behind first-place Minnesota.


The White Sox won three of 5 matches in a rare five-game series with the Royals owing to the season’s delayed start, including a 7-4 victory on Thursday afternoon.


Luis Robert homered and drove in four runs to help the White Sox win the series and return to .500 before traveling to the Bronx. The victory marked Chicago’s sixth comeback victory of the year.


Despite a series of injuries to begin the season, the White Sox are able to stay in the AL Central competition. They’ve been without starting pitcher Lance Lynn since the beginning of the season due to a knee injury, lost OF Eloy Jimenez to a serious hamstring injury on May 10th, and only recently regained the services of 3B Yoan Moncada, who only appeared in 9 matches this season.


In Saturday’s matinee, Chicago will rely on veteran left-hander Keuchel to get them off to a good start.


  • The total went UNDER in 5 of Chi White Sox’s previous 7 matches.
  • The White Sox are 1-5 SU in their last 6 matches against NY Yankees.
  • The Chicago White Sox are 8-2 SU in their last 10 matches on the road.

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Chicago White Sox vs New York Yankees Predictions 5/21/2022


Despite dropping the last game of their four-game series in Baltimore, the Yankees remain atop the American League standings. The Yankees had a major league-best 28-10 record entering this series, including a 14-4 record at Yankee Stadium.


The Yankees lost their second match in 11 appearances on Thursday, as Anthony Santander hit a 3-run walk-off home run in the ninth inning to give Baltimore a 9-6 win. It was the Yankees’ first defeat in 19 matches in which they scored five or more runs. After a 6-2 road trip, New York comes home.


For the second time in less than a week, the Bronx Bombers will face Keuchel. In the first battle, they only managed 4 hits and failed to score a run against the experienced lefty. This year, New York has a. 253 team batting average against left-handed pitching at home, with 8 home runs and 18 extra-base hits.


This year, they have a 92 percent winning record against left-handed pitching. Cortes, the starter on Saturday, was a revelation since entering the Yankees’ rotation last year. Nestor went 2-3 with a 3.07 ERA and 75 strikeouts in 14 starts in 2021, pitching 73.1 innings and allowing just 65 hits.


  • The NY Yankees are 9-2 SU in their previous 11 matches.
  • The Yankees are 11-1 SU in their previous 12 home matches.
  • The total went UNDER in 5 of the NY Yankees’ last 5 matches against the Chi White Sox.

Chicago White Sox vs New York Yankees. The MLB pick for this game is the New York Yankees. Nestor Cortes’ sample size expanded to the point where he can no longer be considered anything less than a great left-handed starter.


In just 113 innings, he struck out 124 hitters in 21 starts. Keuchel pitched well in his previous two starts, but he struggled all season and may get shelled if he can’t keep the ball down.


In game one of this series, the Yankees should cruise to a multi-run victory. The New York Yankees will win by a predicted score of 6-5.


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Chicago White Sox vs New York Yankees 5/21/2022 Picks Predictions Previews

MLB Starting Time: 1:05 PM (EDT)


Location: Yankee Stadium, NY


Date: Saturday, May 21, 2022




MLB Odds: New York Yankees -185


MLB Totals: 8.5


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