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Arizona Cardinals vs Detroit Lions 12/19/2021 Picks Predictions Previews

Arizona Cardinals vs Detroit Lions 12/19/2021 Picks Predictions Previews


The Arizona Cardinals will meet the Detroit Lions at the Ford Field in Detroit, Michigan on Sunday, December 19, 2021, at 1:00 PM ET.  The Cardinals are currently first in the NFC West standings with a record of 10-3. The team snapped its third winning streak last Monday to the Los Angeles Rams to a score of 23-30.


Arizona’s defense surrendered 356 total yards to the Rams. Kyler Murray put up 383 passing yards but was intercepted two times. The Cardinals rolled up 447 yards of total offense but made two turnovers. James Conner scored twice on the ground. Isaiah Simmons and Jordan Hicks surrendered receptions on four of their six targets. 


The Cardinals passed for 252.2 yards and rushed for 122.5 yards. Quarterback Kyler Murray made a total of 2,782 passing yards while running back James Conner delivered 661 rushing yards. Wide receiver Christian Kirk leads the receivers with 718 yards. Linebacker Jordan Hicks leads the team’s defense with 101 tackles and cornerback Byron Murphy Jr. intercepted four passes for the team.


  • The total went OVER in 6 of Arizona’s last 6 matches on the road against Detroit.
  • The Arizona Cardinals are 7-0 ATS in their last 7 matches on the road.
  • The Cardinals are 10-3 SU in their last 13 matches.

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Arizona Cardinals vs Detroit Lions Predictions 12/19/2021


The Detroit Lions are fourth in the NFC North standings this season and have a record of 1-11-1. The team lost its game last Sunday against the Denver Broncos to a score of 10-38. Jared Goff completed 24 of 39 passes for 5.5 yards per attempt.


Godwin Igwebuike finished with just eight attempts for 25 yards. Craig Reynolds delivered 11 carries and gained 83 yards. Detroit surrendered 358 yards of total offense and rolled up 316 yards, committing two turnovers. 


The Lions passed for 200.8 yards and rushed for 110.5 yards this year. Quarterback Jared Goff has a total of 2,791 passing yards and running back D’Andre Swift rushed for 555 total yards. Tight end T.J. Hockenson leads the receivers with 583 yards. Safety Tracy Walker III leads the team’s defense with 78 tackles while CB Amani Oruwariye intercepted five passes for the team.


  • The total went OVER in 12 of Detroit’s last 17 matches against Arizona.
  • The total went OVER in 6 of Detroit’s last 6 matches at home against Arizona.
  • The Lions are 1-9 SU in their last 10 matches at home.

Arizona Cardinals vs Detroit Lions. The NFL’s pick is the Arizona Cardinals. The Lions played well against the spread versus the Cardinals and managed to cover the number in their last seven home matches and four of their last five overall.


Meanwhile, Arizona plays better than Detroit but failed to cover the nut in five of its last six matches. Look for the Arizona Cardinals to win on the road with a predicted score of 28-17.


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Arizona Cardinals vs Detroit Lions 12/19/2021 Picks Predictions Previews

NFL Starting Time: 1:00 PM ET 


Location: Ford Field


Date: Sunday, December 19, 2021




NFL Odds: Arizona Cardinals -13


NFL Totals: 47.5 


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