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San Francisco 49ers vs Seattle Seahawks 12/5/2021 Picks Predictions Previews

San Francisco 49ers vs Seattle Seahawks 12/5/2021 Picks Predictions Previews


The San Francisco 49ers will invade Washington State to clash with the Seahawks at Lumen Field in Seattle on Sunday afternoon. San Francisco is on a 3-game winning run after routing the visiting Minnesota Vikings to a score of 36-24 at Levi’s Stadium in Santa Clara, CA, Sunday.


The favorite 49ers have a shot to end their road struggles against the slumping Seahawks. The 49ers improved to 3-0 SU and ATS over their last three games and are now 4-1 SU and ATS over their last five since going 0-4 SU and ATS in their previous four games. The SF 49ers are 3rd at 6-5in the National Football Conference West Division.


QB Jimmy Garoppolo hurled 2,342 yards, 13 touchdowns, and 8 picks on 66.8% passing while RB Elijah Mitchell leads the 49ers’ ground assault with 693 rushing yards and 4 scores.


WR Deebo Samuel leads the Niners in receiving with 56 grabs for 1006 yards and 5 TDs while Brandon Aiyuk and George Kittle each have 400+ receiving yards as well this season. The defense saw Fred Warner leading the 49ers with 92 total tackles while Nick Bosa has a team-high 11 sacks on the year.


  • The San Francisco 49ers are 5-15 ATS in their last 20 games against the Seahawks.
  • San Francisco is 2-14 SU in their last 16 games against Seattle.
  • The 49ers are 5-1 SU in their last 6 games down the road.

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San Francisco 49ers vs Seattle Seahawks Predictions 12/5/2021


In Seattle, The Seahawks are 2-8 in their last 10 matches of the season and lost 3 consecutive matches. The Washington Football Team edged the visiting Seahawks to a score of 17-15 at FedEx Field in Prince George’s County, Maryland, Monday.


QB Russell Wilson went 20-for-31 with 247 passing yards, 2 TD, and no interceptions – he threw an interception on a late two-point conversion attempt for a tie but did not count in the game.


Russell Wilson is back healthy for the Seahawks having completed 124-191 passes on the year for 1,564 yards, and10 touchdowns and three interceptions so far.


Running the ball in place of injured Chris Carson is Alex Collins. Collins has 94 carries for 381 yards and two touchdowns. Wilson also led the team in rushing with 16 yards as Seattle’s running backs and rushed for a total of only 18 yards on 10 combined attempts in their recent loss.


  • The total went OVER in 5 of Seattle’s last 7 games against the San Francisco 49ers.
  • The Seattle Seahawks are 1-5 SU in their last 6 games at home.
  • Seattle is 9-1 SU in their last 10 games when playing at home against San Francisco.

San Francisco 49ers vs  Seattle Seahawks. The NFL pick for this game is the San Francisco 49ers. San Francisco will have to maintain their playing form on defense and are rushing the ball effectively.


This is their formula to winning matches and should lead to a win and cover if it continues against the Seahawks. Prediction: San Francisco will win at 27-21.


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San Francisco 49ers vs Seattle Seahawks 12/5/2021 Picks Predictions Previews

NFL Starting Time: 4:25 PM (EDT)

Location: Lumen Field in Seattle, WA

Date: Sunday, December 5, 2021


NFL Odds: San Francisco 49ers -3.5

NFL Totals: 45.5


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