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Buffalo Bills vs New Orleans Saints 11/25/2021 Picks Predictions Previews

Buffalo Bills vs New Orleans Saints 11/25/2021 Picks Predictions Previews


The Buffalo Bills will invade the Mercedes-Benz Superdome in New Orleans, Louisiana to go against the New Orleans Saints on Thursday, November 25, 2021, at 8:20 PM ET. The Bills are currently second in the AFC East standings with a record of 6-4.


The team lost to the Indianapolis Colts last Sunday to an ugly score of 15-41. The team rolled up 307 yards of total offense, committing four turnovers. Josh Allen earned his second-worst passing grade this season and dropped five passes.


Matt Breida put up two rushing first downs and an explosive play on five carries. Stefon Diggs cranked two touchdowns on four catches. The team’s defense surrendered 185 yards rushing and four touchdowns on the ground. 


The Bills passed for 273.3 yards and rushed for 118.8 yards this season. Quarterback Josh Allen has a total of 2,811 passing yards while running back Devin Singletary rushed for 415 total yards.


Wide receiver Stefon Diggs leads the receiving team with 773 yards. The team’s defensive unit is led by safety Jordan Poyer who has 56 tackles and he also intercepted four passes for the Bills.


  • The total went OVER in 4 of Buffalo’s last 6 matches.
  • The Buffalo Bills are 14-5 SU in their last 19 matches.
  • The Bills are 0-5 ATS in their last 5 matches against New Orleans.

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Buffalo Bills vs New Orleans Saints Predictions 11/25/2021


The New Orleans Saints rank second in the NFC South standings this year with a 5-5 overall record. The Saints are coming into this match with three consecutive defeats. The team lost to the Philadelphia Eagles last Sunday to a score of 29-40.


The team surrendered 380 yards of total offense and gained 323 yards, committing three turnovers. Mark Ingram II gained 88 yards with 72 coming after contact. Ingram added 25 yards on six catches. Adam Trautman caught five of his eight targets for 58 yards. 


The Saints passed for 203.4 yards and rushed for 117.9 yards. Quarterback Jameis Winston has a total of 1,170 passing yards while running back Alvin Kamara rushed for 530 yards.


Wide receiver Deonte Harris leads the receivers with 418 yards and linebacker Demario Davis leads the team’s defense with 66 tackles. Cornerback P.J. Williams delivered three interceptions for New Orleans.


  • The New Orleans Saints are 8-4 SU in their last 12 matches at home.
  • The total went OVER in 4 of New Orleans’ last 5 matches this season.
  • The Saints are 14-3 SU in their last 17 matches against an opponent in the American Football Conference conference.

Buffalo Bills vs New Orleans Saints. The NFL’s pick is the Buffalo Bills. Buffalo lost its first rank and dropped to second after losing against the Colts.


However, the Bills will manage to bounce back in this match against New Orleans, who are currently struggling to win a home match. Look for the Buffalo Bills to win on the road with a predicted score of 27-17.


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Buffalo Bills vs New Orleans Saints 11/25/2021 Picks Predictions Previews

NFL Starting Time: 8:20 PM ET 


Location: Mercedes-Benz Superdome 


Date: Thursday, November 25, 2021




NFL Odds: Buffalo Bills -6.5


NFL Totals: 45


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