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Arizona Cardinals vs Seattle Seahawks 11/21/2021 Picks Predictions Previews

Arizona Cardinals vs Seattle Seahawks 11/21/2021 Picks Predictions Previews


The Seattle Seahawks will battle against the Arizona Cardinals in NFC West action in Lumen Field, Seattle, on Sunday, November 21, 2021, at 04:25 PM (EDT). 


The Arizona Cardinals are 8-2 and are in the lead in the NFC West while the Seattle Seahawks are 3-6, in last place.  The Cardinals are tied with the Green Bay Packers for the top position in the National Football Conference.


After starting the season with 8 consecutive wins, the Cardinals took their second loss last week.  Arizona was shut out by the Carolina Panthers in the first half.  Colt McCoy completed 11 of 20 for 107 yards and an interception.  McCoy replaced Kyler Murray for the second straight game due to injury. 


Third-string quarterback Chris Streveler finished the game when McCoy left the game in the third quarter.   Arizona posted a total of 249.7 passing yards which is top 12 and 125.8 rushing yards which is top 8 in the NFL for a total of 395.9 yards. 


The Cardinals allowed 221.3 pass yards and 116.6 rush yards for a total of 337.9 yards allowed.  QB Kyler Murray leads the Cardinals with 2276 passing yards, 17 TDS, and 7 INTs.  RB James Conner leads with 493 rushing yards and 11 TDs while WR Christian Kirk leads with 603 receiving yards and 4 TDs. 


In defense, LB Jordan Hicks posted a team-high 74 tackles while CB Byron Murphy Jr. leads with 3 interceptions.  


  • The Arizona Cardinals are 5-2 ATS in its last 7 matches against Seattle.
  • The Cardinals are 2-4 SU in its last 6 matches against the Seahawks.
  • Arizona is 5-1 ATS in its last 6 road games against Seattle.

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Arizona Cardinals vs Seattle Seahawks Predictions 11/21/2021


The Seattle Seahawks look to rebound from their loss against the Green Bay Packers.  Last week, the Seattle Seahawks were shut out by the Packers 17-0.  Seattle threw away two chances of scoring when Kevin King and Adrian Amos picked off Russell Wilson’s passes in the end zone.    


This season, Seattle averages 202.4 passing yards which is ranked 30th, and 99.8 rushing yards, ranked 22nd in NFL for a total of 328.6 yards.  Seattle allowed 287.7 pass yards and 125.2 rush yards for a total of 412.9 yards allowed. 


QB Russell Wilson leads the Seattle Seahawks with 1357 passing yards, 10 TDs, and 3 INTs.  RB Alex Collins leads with 345 rushing yards and 2 TDs while WR DK Metcalf leads with 606 receiving yards and 8 TDs.  In defense, LB Bobby Wagner posted a team-high 101 tackles while S Quandre Diggs led with 3 interceptions.


  • The total went UNDER in 4 of Seattle’s last 6 matches against Arizona.
  • The Seattle Seahawks are 1-4 SU in its last 5 home games.
  • Seattle is 1-5 ATS in its last 6 home games against Arizona.

Arizona Cardinals vs Seattle Seahawks. The NFL pick for this game is the Arizona Cardinals.  The Seattle Seahawks continue to struggle and have only won a game at home this season. 


Arizona averages 28.7 ppg versus 20.1 from Seattle.  Despite the recent two losses, Arizona will rebound in this game and outmatch Seattle.  The Arizona Cardinals will win on the road to a predicted score and cover ATS 27-24.


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Arizona Cardinals vs Seattle Seahawks 11/21/2021 Picks Predictions Previews

NFL Starting Time: 4:25 PM (EDT)


Location: Lumen Field, Seattle, USA


Date: Sunday, November 21, 2021




NFL Odds: Arizona Cardinals -2.5


NFL Totals: 50.0


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