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Oklahoma State Cowboys vs Iowa State Cyclones 10/23/2021 Picks Predictions Previews

Oklahoma State Cowboys vs Iowa State Cyclones 10/23/2021 Picks Predictions Previews


The #12 Oklahoma State Cowboys will meet with the Iowa State Cyclones in NCAAF action in Jack Trice Stadium, Ames, on Saturday, October 23, 2021, at 3:30 PM (EDT). Oklahoma State is returning from a weekend showdown with Texas. The Cowboys won that game by an eight-point margin. Despite a few close calls, Oklahoma State is off to a good start this season. The Cowboys defeated Missouri State 23-16 in their first game, then Tulsa 28-23 and Boise State 21-20 in their next three games.


After that, they won two more games, 31-20 against Kansas State and 24-14 against Baylor. Oklahoma State fell behind 24-16 in the fourth quarter of last weekend’s huge game against Texas but rallied 16 unanswered points to win 32-24. Spencer Sanders had 178 yards, one touchdown, and one interception. With 193 yards on 33 carries, Jaylen Warren topped the rushers.


  • The #2 Oklahoma State Cowboys are 4-1 ATS in their last 5 matches.
  • The #2 Oklahoma State Cowboys are 8-1 SU in their last 9 matches against Iowa State.
  • The total went UNDER in 6 of Oklahoma State’s last 6 matches on the road.

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Oklahoma State Cowboys vs Iowa State Cyclones Predictions 10/23/2021


Iowa State’s most recent match was against Kansas State. The Cyclones won by 13 points in that game. Iowa State had a 2-2 record in their first four matches. Northern Iowa 16-10 and UNLV 48-3 were the victories, while Iowa 27-17 and Baylor 31-29 were the defeats. On October 2, the Cyclones defeated Kansas 59-7 to return to.500 on the season.


Iowa State had a 20-7 lead in the first half against Kansas State and held on for a strong 33-20 victory. QB Brock Purdy completed 22 of 25 passes for 208 yards and a touchdown, and Breece Hall rushed for 197 yards and two touchdowns on 30 attempts.


  • The #4 Iowa State Cyclones are 10-3 SU in their last 13 matches.
  • The total went OVER in 4 of Iowa State’s last 6 matches against Oklahoma State.
  • The #4 Iowa State Cyclones are 7-1 SU in their last 8 matches at home.

#2 Oklahoma State Cowboys vs #4 Iowa State Cyclones. The NCAAF pick for this game is the #2 Oklahoma State Cowboys. I’m sticking with Oklahoma State. In the Texas game, the Cowboys played with fire, but to their credit, they rallied in a huge fourth quarter to take the win. Oklahoma State had 398 total yards, 25 first downs, and a 4.9-yard-per-play average.


Iowa State, on the other hand, was steady in their last game, scoring in each quarter on route to 418 total yards and a 7.0-yard average. Because of their large lead, the Cyclones were able to relax on defense in the fourth quarter. The game against Oklahoma State this weekend will be a much stiffer challenge, and I expect Iowa State to stay up with them at first. It should be an entertaining matchup. The #2 Oklahoma State Cowboys will win to a predicted score of 28-20.


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Oklahoma State Cowboys vs Iowa State Cyclones 10/23/2021 Picks Predictions Previews

NCAAF Starting Time: 3:30 PM (EDT)

Location: Jonah Field At War Memorial Stadium, Laramie, WY, USA

Date: Saturday, October 23, 2021


NCAAF Odds: Iowa State Cyclones -7

NCAAF Totals: 47


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