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Ohio State Buckeyes vs Indiana Hoosiers 10/23/2021 Picks Predictions Previews

Ohio State Buckeyes vs Indiana Hoosiers 10/23/2021 Picks Predictions Previews


The No. 5 – ranked Ohio State Buckeyes are gearing up to pay the Indiana Hoosiers a visit as they engage in NCAA football action at the Memorial Stadium in Indiana.  Following a bye week, the Ohio State Buckeyes are coming in with an improved record of 5-1 after defeating the Maryland Terrapins by a score of 66-17 during Week 6.


The Buckeyes earned a total of 598 offensive yards and managed to keep Maryland to just 335 total offensive yards and a pair of forced turnovers.  In this game, quarterback CJ Stroud threw for 406 yards to go along with five passing touchdowns. 


Stroud led the way for Ohio State with 1,699 passing yards, including 104 completions out of 157 attempts, 18 touchdowns, and three picks.  Leading the rushing offense is running back TreVeyon Henderson, who gathered 612 yards and nine touchdowns overall, while Garrett Wilson is team’s lead receiver with 31 receptions on 546 yards and six touchdowns. 


Defensively, safety Ronnie Hickman posted a team-high record in tackles with 50, just as defensive tackle Tyleik Williams had the most quarterback sacks posted with 4.0. 


  • The total went OVER in nine of the Ohio State Buckeyes’ 12 previous matches.
  • Ohio State is at 12-2 SU in 14 of their previous games.
  • The Buckeyes are at 2-8 ATS against the Indiana Hoosiers. 

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Ohio State Buckeyes vs Indiana Hoosiers Predictions 10/23/2021


On the Indiana Hoosiers‘ end, the team further dropped their mark to 2-4 after suffering a home loss against the Michigan State Spartans at 20-15.  Indiana kept the Spartans to just 241 yards of offense overall but was merely able to earn 322 total offensive yards, along with three turnovers. 


In this game, quarterback Jack Tuttle threw for 188 yards and a pair of interceptions, while running back Stephen Carr gathered 53 rushing yards for Indiana and a lone touchdown. 


Tuttle played in place of initial quarterback Michael Penix Jr., who sustained an injury.  The backup QB posted a total of 356 passing yards with a completion percentage of 51.4.  The rushing offense was led by Carr with 439 yards and four touchdowns, while the leader in receptions is Ty Fryfogle, having caught 33 on 337 yards and a single score.


In terms of defense, the team’s leading tackler is linebacker Cam Jones with 35, while lineman Ryder Anderson posted a team-high number of sacks with 3.5 overall.


  • The Indiana Hoosiers are at 1-6 ATS in seven of their previous matches.
  • The total went UNDER in six of Indiana’s nine previous games.
  • The Hoosiers are at 2-5 SU in seven of their previous matches. 

#5 Ohio State Buckeyes vs Indiana Hoosiers. The NCAAF pick is the No. 5 ranked Ohio State Buckeyes at -19.  Ohio State will dominate over Indiana in this Saturday’s matchup, with the play going OVER.  The OVER paid out each of the four last games between these two rivals. 


Moreover, the OVER paid out Ohio State’s six out of their last eight games played in the Big Ten Conference, while it cashed in Indiana’s 13 of 18 when played against a team with a winning record. Ohio State ranks seventh in terms of scoring with 48.5 points per contest.  Final Score Prediction, the Ohio State Buckeyes win with the play going OVER at 42-20.


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Ohio State Buckeyes vs Indiana Hoosiers 10/23/2021 Picks Predictions Previews

NCAAF Starting Time: 7:30 PM EDT


Location: Memorial Stadium Bloomington, Indiana


Date: Saturday, October 23, 2021




NCAAF Odds: Ohio State Buckeyes -19


NCAAF Total Odds: 60.5


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