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Cincinnati Reds vs Chicago White Sox 9/28/2021 Picks Predictions Previews

Cincinnati Reds vs Chicago White Sox 9/28/2021 Picks Predictions Previews


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The Guaranteed Rate Field will play host to Game one of a doubleheader between the Chicago White Sox and Cincinnati Reds on Tuesday night.  The Reds are in third place in the NL Central Division at 82-75 and are still a contender in the NL Wild-Card Chase.  The Chicago White Sox clinched the Division as the leader of AL Central at 89-68.   


The Cincinnati Reds are riding on a four-game winning streak.  The Reds defeated the Pirates with a 13-1 blowout and won the last three games against the Nationals after dropping the series opener.  The Reds are vying for the second Wild Card Spot but are 5 ½ games behind the St. Louis Cardinals for the position.  Cincinnati has an on-base percentage of .330 which improved to the top 8 and is batting at an average of .251 which improved to the top 6 in MLB.  Their 770 total runs scored improved to the top 7 in the league.  The team is below average at the mound with a 4.32 ERA which dropped to 18th and a BAA of .242 is 15th in the league.  For the opener on Tuesday, Cincinnati will send Riley O’Brien to the hill.  Riley O’Brien will be called up from Triple-A Louisville to make his major league debut and replace Luis Castillo who was placed on a family emergency leave. 


  • The Cincinnati Reds are 4-2 SU in its last 6 games against the Chicago White Sox.
  • Cincinnati is 1-5 SU in its last 6 games on the road against the Chicago White Sox.
  • The total went OVER in 6 of Cincinnati’s last 8 games.

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Cincinnati Reds vs Chicago White Sox Predictions 9/28/2021


The Chicago White Sox looks to extend their two-game winning streak.  Eloy Jimenez hit a two-run homer and Yasmani Grandal homered to spark a six-run fourth inning.  The White Sox held off and defeated the Tigers at 8-7.  The White Sox split their last 10 games.  Chicago’s offense has been solid with a batting average of .256 which is top 5 and 768 runs scored which is top 8 in MLB.  Their OBP of .335 is top 3 in the league.  The Pitching team dropped to top 7 with a 3.77 ERA and top 6 with 1.21 WHIP.  Their .230 BAA dropped to top 6 in MLB.  Given the starting role in Tuesday’s game is Reynaldo Lopez.  The right-hander is 3-3 with an ERA of 3.16 and struck out 51 batters in over 51 innings. 


  • The Chicago White Sox are 10-5 SU in its last 15 games at home.
  • Chicago is 5-1 SU in its last 6 games at home against Cincinnati.
  • The total went UNDER in 4 of the White Sox’s last 5 games against Cincinnati.

Cincinnati Reds vs Chicago White Sox. The MLB pick for this game goes to the Chicago White Sox.  Cincinnati pretty much ended their hopes for a wild-card spot.  Chicago has locked in their spot in the playoffs but with a young team needing more experience, look to Chicago to build more wins on the road to the playoffs.  Taking the game at home is the Chicago White Sox.  Final Score Prediction is 4-3.  


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Cincinnati Reds vs Chicago White Sox 9/28/2021 Picks Predictions Previews

MLB Starting Time: 8:10 PM ET


Location: Guaranteed Rate Field, Chicago


Date: Tuesday, September 28, 2021




MLB Odds: Chicago White Sox -175


MLB Totals: 9.5


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