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St Louis Cardinals vs Chicago Cubs 9/25/2021 Picks Predictions Previews

St Louis Cardinals vs Chicago Cubs 9/25/2021 Picks Predictions Previews


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The St. Louis Cardinals will play Game 3 of their 4-game weekend rivalry series against the Chicago Cubs at the Wrigley Field, Chicago, IL, on Saturday, September 25, 2021, at 7:10 PM (EDT). The Cardinals are coming to this match looking to build on their 3-run victory during the Friday opener’s doubleheader versus the Milwaukee Brewers followed by another big victory in the nightcap. St.Louis moved to an 85-69 record on the year, sitting 2nd in the National League Central Division.


IF Tommy Edman has a total of 160 hits to lead the Cardinals while 3B Nolan Arenado shares the lead with 145 hits and a team-best 33 homers. St. Louis will turn to southpaw Jon Lester to throw the starting pitch in this matchup and he is on a 7-6 record with an ERA of 4.59.


  • The St.Louis Cardinals are 9-0 SU in their last 9 games down the road.
  • The total went OVER in 5 of St. Louis’ last 7 games down the road against the Chi Cubs.
  • The St.Louis Cardinals are 14-0 SU in their last 14 games this season.

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St Louis Cardinals vs Chicago Cubs Predictions 9/25/2021


Over at the Chicago camp, the Cubs are approaching this match after both of their contests against Minnesota earlier this week. Chicago has lost 8 of their last 10 games overall and the team is on a 67-87 record on the year, sitting 4th in the National League Central Division.


CF Ian Happ leads the Cubs’ lineup with 98 hits with a batting average of .226 average, 23 homers while Catcher Wilson Contreras shares the lead with 89 hits. For the Saturday game, Adrian Sampson will take the mound to make his 4th start of the season for the Cubs. He is 1-2 with a 2.84 ERA across 25.1 innings in 8 games and 2 starts this season.


  • The total went OVER in 6 of the Chi Cubs’ last 6 games at home.
  • The total went OVER in 5 of the Chi Cubs’ last 7 games at home against St. Louis.
  • The Chi Cubs are 2-11 SU in their last 13 games this season.

St. Louis Cardinals vs Chicago Cubs. The MLB pick for this contest is the Chicago Cubs. The Cardinals are playing their best baseball of the season but the Cubs will own this game. Chicago’s Adrian Sampson has pitched very well over his last three outings, posting a total of 6 earned on 4 hits and 4 walks in 14.0 innings and the team ranks 20th in OPS and 20th in runs scored. The Chicago Cubs will take the win at home to a predicted score of 6-3.


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St Louis Cardinals vs Chicago Cubs 9/25/2021 Picks Predictions Previews

MLB StartingTime : 7:10 PM (EDT)


Location: Wrigley Field, Chicago, IL


Date: Saturday, September 25, 2021




MLB Odds: Chicago Cubs +150


MLB Totals: 10.5


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