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San Francisco Giants vs San Diego Padres 9/23/2021 Picks Predictions Previews

San Francisco Giants vs San Diego Padres 9/23/2021 Picks Predictions Previews


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The San Francisco Giants will conclude their 3-game series finale with the Padres in the NL West battle at Petco Park in San Diego on Thursday, September 23, 2021, at 10:10 PM ET. San Francisco was victorious in Games 1 and 2 to scores of 6-5 and 8-6, respectively. Frisco’s 2nd straight victory over the Priests extended the gap with the LA Dodgers at 99-53 to keep their lead in the National League West Division.


The Giants are 7-3 in their last 10 matches on the season and they are one of the best offensive teams in the majors at 4th fourth place with a .771 OPS this season. San Fran has a .871 OPS with 6.08 runs per game in that stretch in their last 12 games. SS Brandon Crawford has been hitting well with a .893 OPS with 21 homers and 82 RBI with 10 stolen bases in 13 attempts. The Giants can maintain their lead in the NL West if they continue to be offensively hot.


  • San Francisco is 6-3 SU in their last 9 games against San Diego.
  • The San Francisco Giants are 7-0 SU in their last 7 games on the road.
  • The Giants are 7-3 SU in their last 10 games this season.

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San Francisco Giants vs San Diego Padres Predictions 9/23/2021


Meanwhile, the San Diego Padres are16th in MLB with a .722 OPS. The team was able to score runs in bunches with an average of 4.53 runs per game this year. In September, the Padres struggled with an average of 3.88 runs per game with a team slashline of .257/.317/.399 in their 17 matches this month. San Diego is in 3rd place with a win/loss slate 0f 76-75 in the NL West.


The Padres are on a 5-game losing slump and are on the verge of a sweep-off in their 3-game series by the Giants. SS Fernando Tatis Jr has a .986 OPS with 39 home runs and 93 RBI while stealing 25 bases on 29 attempts. If the Padres can raise their bars on their remaining slugfests, they can make a last-ditch effort to make the NL Wild Card slot. 


  • The total has gone OVER in 10 of San Diego’s last 11 games with the Giants.
  • San Diego is 3-8 SU in their last 11 games at home.
  • The total went OVER in 4 of San Diego’s last 5 games at home against San Francisco.

San Francisco Giants vs. San Diego Padres. The MLB Pick for this game is the San Francisco Giants. The San Diego Padres nudged off the diamond down the stretch while the Giants are in their top form at this point of the competition. Logan Webb is 5-2 with a 2.49 ERA while Yu Darvish is 7-6 with a 3.86 ERA in 19 night-starts. San Francisco will win this contest predicted to a score of 5-3.


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San Francisco Giants vs San Diego Padres 9/23/2021 Picks Predictions Previews

MLB Starting Time: 10:10 PM ET


Location: Petco Park in San Diego, CA


Date: Thursday, September 23, 2021




MLB Odds: San Francisco Giants -103


MLB Totals: 8.5


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