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San Francisco Giants vs San Diego Padres 9/22/2021 Picks Predictions Previews

San Francisco Giants vs San Diego Padres 9/22/2021 Picks Predictions Previews


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The San Francisco Giants will bash it out with the Padres in Game 2 of the NL West three-game battle at Petco Park in San Diego on Wednesday, September 22, 2021, at 10:10 PM ET. San Francisco won Game 1 over San Diego to a score of 6-5 yesterday evening. San Francisco rallied from a 4-1 deficit to take a 5-4 lead in the sixth against Joe Musgrove. Brandon Crawford doubled in Kris Bryant with the tying run and then scored the go-ahead run on Mike Yastrzemski’s sacrifice fly. The Giants are now 98-53 and still leading the National League West Division by a game over the Dodgers.


The Giants are 7-3 in their last 10 matches and scored 8 runs in their last 3 games and 4 or more runs in 7 of their last 9 games. SS Brandon Crawford leads the Giants with 132 hits and 82 RBI while Catcher Buster Posey and RF Mike Yastrzemski totaled 205 hits and 107 RBI. Scott Kazmir gets the ball; he is 0-1 with a 6.43 ERA and seven Ks this season. Kazmir is 1-0 with a 4.91 ERA and 32 Ks in his career against the Padres.


  • San Francisco is 6-3 SU in their last 9 games against San Diego.
  • The San Francisco Giants are 7-0 SU in their last 7 games on the road.
  • The Giants are 7-3 SU in their last 10 games this season.

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San Francisco Giants vs San Diego Padres Predictions 9/22/2021


In “America’s Finest City”, the San Diego Padres suffered their 4th straight loss in Game 1 of 3 to the San Francisco Giants yesterday; the St. Louis Cardinals recently swept the Padres in their 3-game series finale of the regular season. San Diego is currently 3rd in the NL West Division with a win/loss tally of 76-74.


San Diego is 3-9 in their last 12 matches on the season. The Padres lost for the ninth time in 11 games, dropping them from a one-game lead for the second wild-card spot to five games behind the Cardinals, with the Reds a game ahead of them and the Phillies a half-game ahead. Vince Velasquez gets the ball; he is 3-7 with a 6.09 ERA and 89 Ks this season. Velasquez is 1-4 with a 4.02 ERA and 38 strikeouts in his career against the Giants.


  • The total went OVER in 9 of San Diego’s last 10 games with the Giants.
  • San Diego is 3-7 SU in their last 10 games at home.
  • The total went OVER in 4 of the Padres’ last 5 games this season.

San Francisco Giants vs. San Diego Padres. The MLB Pick for this game is the San Francisco Giants. The Giants are superb on all sides of the diamond and will continue to bash the Padres in this match. San Francisco has the advantage in its bullpen over San Diego. Take the Giants to crush the priests predicted to a score of 8-5.


MLB Free Premium Picks Predictions. Today’s entire Major League Baseball premium pick predictions are free right now at 1-888-711-4311 or text the word WINBIG to 760-670-3130 to receive them. Included are Best Bets, Totals, Parlays and First Five Inning winners for today free of charge.


San Francisco Giants vs San Diego Padres 9/22/2021 Picks Predictions Previews

MLB Starting Time: 10:10 PM ET


Location: Petco Park in San Diego, CA


Date: Wednesday, September 22, 2021




MLB Odds: San Francisco Giants -120


MLB Totals: 9.5


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