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Arizona Cardinals vs Tennessee Titans 9/12/2021 Picks Predictions Previews

Arizona Cardinals vs Tennessee Titans 9/12/2021 Picks Predictions Previews


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The Arizona Cardinals will meet with the Tennessee Titans in NFL action in Nissan Stadium, on Sunday, September 12, 2021, at 1:00 PM (EDT). Arizona had a promising but unsuccessful 2020 campaign, ending 8-8 after starting the year 6-3. The team’s progression was halted by Kyler Murray’s midseason shoulder injury, but this is a roster that is ready to compete in 2021. The offensive efficiency is the main draw, but the defense was bolstered by the additions of Malcolm Butler, JJ Watt, and first-round selection Zaven Collins, despite the departure of a fading Patrick Peterson in the secondary.


In an otherwise even battle, can Arizona intend to stop two-time defending NFL running champion, Derrick Henry? We’re not certain after its defensive performance was ranked 11th in the nation in halting the run in 2020. We do understand that the Cardinals’ offense will most likely improve this year.


  • The Arizona Cardinals are 2-7 ATS in their previous 9 matches.
  • The Cardinals are 5-1 ATS in their last 6 matches against Tennessee.
  • The total went UNDER in 6 of Arizona’s last 6 matches on the road.

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Arizona Cardinals vs Tennessee Titans Predictions 9/12/2021


Last season, Tennessee dominated a mediocre AFC South division, going 11-5 in the playoffs before being knocked out in the Wild Card round by Baltimore. Now, despite the major signing of Julio Jones, the Titans appear to be entering the upcoming season with an overall weaker squad than last year. The offense will be heavily focused on its three skill position stars, but the defense will continue to be vulnerable.


Last year, Tennessee had the NFL’s third-best run rate. With Julio Jones to toss to and a motivation to relieve some of the weight off Derrick Henry after a tremendous season of touches last year, their run/pass ratio should return towards the median this year. When you consider Henry’s mythological frame and the fact that he has an extra regular-season match to play this year, it’s easy to understand why 30+ touches per game may not be maintainable.


  • The Tennessee Titans are 2-4 ATS in their last 6 matches.
  • The Titans are 2-4 SU in their last 6 matches at home against Arizona.
  • The total went OVER in 11 of Tennessee’s last 15 matches at home.

Arizona Cardinals vs Tennessee Titans. The NFL pick for this game is the Arizona Cardinals. Arizona has a lot of big-play weapons and a quarterback who can complete a drive on his own, despite Ryan Tannehill’s rushing abilities. Pick the Cardinals at +3 and be sure that they will score multiple touchdowns at Nissan Stadium. The Arizona Cardinals will win to a predicted score of 28-24.


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Arizona Cardinals vs Tennessee Titans 9/12/2021 Picks Predictions Previews

NFL Starting Time: 1:00 PM (EDT)


Location: Nissan Stadium, USA


Date: Sunday, September 12, 2021




NFL Odds/Point Spread: Arizona Cardinals +3


NFL Totals: 51.5


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